Vemulapalli V, Bai Y, Kalluri H, Herwadkar A, Kim H, Davis SP, Friden PM, Banga AK. 2005;22(4):5505. The permeability of fluorescein isothiocyanate-dextrans (FITC-dextrans) with different molecular weights through the pig and human cadaver skins were measured using Franz diffusion cell. Dextran. On the molecular weight distribution of dextran T-500. Ioan, C.E. Nanoparticles in magnetic resonance imaging: from simple to dual 2012 Sep 1;90(1):441-6. doi: 10.1016/j.carbpol.2012.05.063. Determination of constants, kM-H and a, from the intrinsic viscosity data, requires a series of monodisperse polymer samples with known molecular weight or a series of polydisperse polymer samples with known viscosity average molecular weights, Mv. As well as being able to measure hydrodynamic radius in the Zetasizer (if you have access to one), it's also provided with a calculator that allows Carbohydr Polym. Kasaai, Mohammad R. (2012). Transdermal delivery of FITC-Dextrans with different molecular weights using radiofrequency microporation, https://doi.org/10.1186/s40824-020-00201-7, http://creativecommons.org/licenses/by/4.0/, http://creativecommons.org/publicdomain/zero/1.0/. Probiotics Antimicrob Proteins. Table 3 shows the intrinsic viscosity for the rest of the dextrans obtained by using the single-point method, measured at different temperatures. 2011;5(2):95132. Die Makromolekulare Chemie, 148(1), 229-238. Format), Citation-(EndNote As intrinsic viscosity of dextrans decreases with an increase in solution temperature; chain flexibility enhances with an increase in temperature (see Table 4) showing that the intrinsic viscosity of dextran (with different molecular weights Mw from 8.8 to 200kDa) decreases linearly with an temperature increase in solution, but change to high molecular weight to hyperbranched macromolecule. After 24h, the cumulative permeation of FITC-dextran M.W. Increased epidermal laser fluence through simultaneous ultrasonic microporation. The increased TEWL values which were proportional to the number of microspores indicate SC disruption and formation of microchannels in the skin. The receptor chamber was filled with PBS. Although, intrinsic viscosity is a molecular parameter that can be interpreted in terms of molecular conformation, it does not offer as high resolution on molecular structure as other methods such as Light Scattering, Circular Dichroism, Sedimentation Velocity, Sedimentation Equilibrium, Size Exclusion Chromatography Coupled to Multi-Angle Laser Light Scattering (SEC-MALLS), High-performance Size Exclusion Chromatography (HPSEC), Gel Permeation Chromatography (GPC), NMR, X-rays, etc. It is worth noting that the size of macromolecules is much bigger than that of solvent (water) molecules [50]. RBECs were passaged onto cell culture inserts as described and cultured for a further 714 days in vitro. (2003). Materiaux 1-5. statement and For a rigid or rod like polymer molecule that is greatly extended in solution, the Mark-Houwink a constant approaches to a value of 2.0 [48].The hydrodynamic radius (RH), for a sphere ((a/b) = 2.5) is given by the Einstein relation [49].

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